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HDAC-8 Antibody
産品編号: CN0830
  • 100.00µg
    ¥2600.00
  • 25.00µg
    ¥815.00
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    詳細介紹

    HDAC-8 Antibody

    Catalog #

    Product Description

    CN0830

    The affinity purified rabbit polyclonal anti-HDAC8 antibody is developed using the C-terminal peptide of human histone deacetylase 8.  It could be used for detection and isolation of HDAC-8.

    Western blot analysis of HeLa cell lysate 10 µg (left) and 30 µg (right) with CN0830.
    Species
    Rabbit
    Formulation
    0.25 mg/mL in TBS, 50% glycerol, 0.01% NaN3
    Immunogen
    Human HDAC-8 (protein code: NP_060956) C-terminal peptide-KLH conjugate
    Purification
    The antibody was purified with antigen-specific immunoaffinity chromatography.
    Specificity
    The antibody recognizes human HDAC-8. It may cross-react with HDAC-8 from other species.
    Applications
    ELISA; WB; IP
    Scientific Description
    Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from the ε-N-acetyl lysine amino acid on histones or other proteins. Its action is opposite to that of histone acetyltransferase.
    HDAC proteins are found in three groups, the first two groups belong to the classical HDACs whose activities are inhibited by trichostatin A (TSA). The third group is a family of NAD+- dependent proteins unaffected by TSA. Homologues to all three groups are found in yeast: reduced potassium dependency 3 (Rpd3) corresponding to class 1, histone deacetylase 1 (hda1) to class 2 and silent information regulator 2 (Sir 2) corresponding to class 3.
    Storage & Stability
    Product is stable for several weeks at 4°C. For extended storage,  store product at –20ºC. Expiration date is three years from date of shipping if properly stored.


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